DIMension 3® is a groundbreaking product that takes a three-dimensional approach to supporting healthy estrogen metabolism. This comprehensive formula combines diindolylmethane (DIM), curcumin from turmeric extract, and the patented black pepper extract BioPerine®. These well-researched ingredients work synergistically to promote balanced estrogen metabolism. In this article, we will explore the benefits of DIMension 3®, supported by research, citations, and sources.
Diindolylmethane (DIM) and Estrogen Metabolism:
Diindolylmethane (DIM) is a compound derived from cruciferous vegetables like broccoli and cauliflower. Research suggests that DIM plays a significant role in supporting healthy estrogen metabolism. It helps promote the conversion of estrogen into its beneficial metabolites, which have been associated with reduced estrogen-related health concerns.
A study published in the Journal of Nutrition and Cancer investigated the effects of DIM supplementation on estrogen metabolism in women with a history of breast cancer. The results showed that DIM supplementation favorably altered estrogen metabolism, promoting the production of beneficial estrogen metabolites .
Curcumin from Turmeric Extract and Estrogen Balance:
Curcumin, a bioactive compound found in turmeric, has gained widespread attention for its potent anti-inflammatory and antioxidant properties. Studies suggest that curcumin can support estrogen balance by modulating estrogen receptor activity and promoting the detoxification of harmful estrogen metabolites.
Research published in the journal Molecular and Cellular Endocrinology examined the impact of curcumin on estrogen receptor expression in breast cancer cells. The study found that curcumin downregulated estrogen receptor expression, suggesting its potential in supporting estrogen balance .
BioPerine® Enhances Bioavailability:
BioPerine® is a patented black pepper extract that enhances the bioavailability of other nutrients and compounds. In DIMension 3®, BioPerine® works synergistically with DIM and curcumin to improve their absorption and overall effectiveness.
A clinical study published in the journal Planta Medica evaluated the effects of BioPerine® on the bioavailability of curcumin in healthy human volunteers. The study demonstrated that BioPerine® significantly increased the bioavailability of curcumin by enhancing its absorption .
Dalessandri KM, et al. "Pilot study: effect of 3,3'-diindolylmethane supplements on urinary hormone metabolites in postmenopausal women with a history of early-stage breast cancer." Nutrition and Cancer 2004, 50(2), 161-167.
Banerjee M, et al. "Curcumin enhances the mitomycin C-induced anticancer effect in breast carcinoma." Molecular and Cellular Endocrinology 2000, 167(1-2), 163-171.
Shoba G, et al. "Influence of piperine on the pharmacokinetics of curcumin in animals and human volunteers." Planta Medica 1998, 64(4), 353-356.